Leg Ulcer

Ulcers always colonised. Antibiotics do not improve healing unless active infection.

If active infection, cleanse wound with tap water or saline to remove surface contaminants. Remove slough and necrotic tissue. Swab viable tissue displaying signs of infection before treatment.

Review antibiotics after culture results.

Active infection if cellulitis/increased pain/pyrexia/purulent exudate/odour.

If active infection

Flucloxacillin 500mg four times daily

For 7 days. If slow response continue for a further 7 days

OR Doxycycline 100mg twice daily

For 7 days. If slow response continue for a further 7 days

Editorial Information

Last reviewed: 23 May 2019

Next review: 23 May 2022

Author(s): Antimicrobial Management Team

Approved By: TAM Subgroup of ADTC

Reviewer Name(s): Area Antimicrobial Pharmacist

Document Id: AMT169