Drugs used in Parkinsonism and related disorders


Refer patients with suspected Parkinson’s disease (PD) early, before beginning treatment, to a clinician with relevant expertise, who should be involved in both initiation and ongoing monitoring of drug therapy. Therapy for PD should be multi-disciplinary; drug treatment is only one aspect. Refer to:
• ’Parkinson’s disease guideline’
• ‘Alternative methods of administration for Parkinson’s disease medicines’
• ‘Inpatient management of Parkinson's including nil by mouth guidance’
• Patient information leaflet, ‘Dopamine agonist medication used to treat Parkinson’s and restless legs’.
• SIGN 113 ‘Diagnosis and pharmacological management of Parkinson’s disease’.

Note: Excessive daytime sleepiness and sudden onset of sleep can occur with dopamine agonists, co-careldopa and co-beneldopa. Warn patients starting treatment with these drugs of the possibility of these effects and of the need for caution when driving or operating machinery.


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